A major redevelopment of the dead end of Brisbane's CBD has been named Queen's Wharf to reflect the area's rich history.

The redevelopment plans involve selling off and redeveloping government and office towers to create a new cultural hub, which includes at least one casino.

Deputy Premier Jeff Seeney unveiled the planned precinct’s name in parliament on Thursday.

“To reflect this rich history, the Queensland government has decided to name the government precinct redevelopment Queen’s Wharf,” he told parliament.

“The name will better reflect the project’s contribution to Brisbane’s emergence as a new world city.”

Mr Seeney says a casino licence and two integrated resort licences will be up for grabs.  Government office buildings in George and Williams streets, including the Executive Building where the premier’s office is located, will be sold off or rebuilt.

New office space would then be leased back by the state government.

There will be a new pedestrian plaza in front of Parliament House, a riverside boardwalk with leisure and entertainment facilities, and a cultural hub.

Mr Seeney said a substantial number of national and international firms had already expressed interest in the project.

The government claimed Queen’s Wharf would create more than 18,000 jobs over the five-year construction period.

A successful developer for the precinct is due to be selected by 2015.